Introduction: Discovering CBD and the digestive system
Cannabidiol, or CBD , has quickly caught on for its therapeutic potential. Although research is still ongoing, preliminary studies suggest that CBD may have several health benefits, including improving digestion and reducing stress. But how does CBD interact with the digestive system and how can it benefit our diet and relieve stress? We will explore these questions in this article.
1: What is CBD and how does it work?
CBD is one of over 100 cannabinoids present in the cannabis plant. Unlike THC, another well-known cannabinoid, CBD is non-psychoactive, meaning it does not produce the "high" effects associated with cannabis. Instead, it interacts with the body's endocannabinoid system, a cell signaling system that regulates a number of biological functions, including digestion.
2: CBD and the endocannabinoid system
The endocannabinoid system (ECS) is made up of endogenous cannabinoids, or endocannabinoids, and the receptors they bind to. These receptors, called CB1 and CB2, are present throughout the body, including the digestive system. CBD has the ability to interact with these receptors, potentially modulating various ECS functions, including gastrointestinal function.
3: CBD and digestion
Recent studies have suggested that CBD may have beneficial effects on the digestive system. Some of these benefits may include reducing intestinal inflammation, improving intestinal motility, and reducing irritable bowel syndrome (IBS) symptoms. In addition, CBD can also help improve nutrient absorption and regulate appetite, which can be beneficial for those struggling with weight problems or health conditions that make it difficult to digest and absorb food properly.
4: Can CBD reduce the desire to eat?
This is an ongoing topic of discussion and the studies are still preliminary, but some indicate that cannabidiol (CBD) might have an effect in reducing appetite. In contrast to its cannabinoid relative, THC, which is known to increase appetite (a phenomenon often referred to as "the munchies"), CBD does not appear to have the same effect.
In a study conducted on rats, researchers found that CBD could have the potential to influence CB1 and CB2 receptors in the brain, both of which are involved in appetite regulation. The study suggests that CBD could possibly help reduce appetite by blocking or "turning off" these receptors.
Furthermore, in a 2018 study published in the journal "JCI Insight", it was found that CBD can reduce motivation for eating in rats, which could suggest an appetite suppressant effect.
5: Understanding the Microbiota
The microbiota , also known as intestinal flora, refers to the community of microorganisms that reside in our body. For the most part, these microorganisms inhabit our gastrointestinal tract, especially the large intestine, although they can also be found in other areas of the body such as the skin, mouth, and vagina.
These microorganisms are incredibly diverse and include bacteria, fungi, protozoa, and viruses, among others. It is estimated that close to 100 trillion microorganisms coexist in the human body, which is ten times the number of human cells. Furthermore, these microorganisms are not mere passive residents; they perform a variety of critical functions that contribute to our health and well-being.
The microbiota plays a vital role in digestion. It helps break down foods, especially those that the body cannot process and break down on its own. Bacteria in the intestine break down dietary fiber into short-chain fatty acids, which can then be absorbed and used by the body. In addition, the microbiota is also responsible for the production of some vitamins, such as vitamins B and K.
However, the function of the microbiota goes beyond digestion. It has also been shown to play a key role in the immune system, helping to protect the body against infection. The microbiota acts as a kind of barrier, preventing pathogenic microorganisms from establishing themselves and causing disease.
Furthermore, there is a growing body of evidence suggesting that the microbiota may also influence mental health. This concept, known as the gut-brain axis, suggests that microorganisms in the gut can affect the brain and behavior through a variety of mechanisms, including neurotransmitter production and modulation of the immune system.
6: CBD, stress and digestion
Stress can have a significant impact on digestive function . When we are stressed, our bodies release stress hormones like cortisol, which can disrupt the function of the digestive system. This can lead to a host of problems, from indigestion to constipation. CBD, with its ability to interact with the ECS and its anti-anxiety properties, can help mitigate these effects of stress on digestion.
7: CBD Products for Digestion
There are several types of CBD products that can be beneficial for digestion. These include CBD oils, capsules, gummies, and teas ( although many of them are not allowed in certain countries like Spain ).
CBD oils and capsules tend to absorb faster and can provide relief more quickly, while gummies and teas can be more palatable and easier to incorporate into your daily routine. There are also flowers for the more traditional and (almost) pure products for those who need something stronger .
Remember that the effectiveness of these products can vary from person to person, and it is always advisable to consult a health professional before starting any new supplement or treatment regimen. And in CBDacasa we have one in case you are interested.
8: CBD, Gut Bacteria, and the Cannabinoid Connection
It is well known that the endocannabinoid system (ECS) plays an important role in regulating various biological functions, including digestion. What is perhaps less well known is the intriguing relationship between the ECS, cannabinoids like CBD , and our gut bacteria, also known as the microbiota .
The human microbiome is incredibly diverse and is estimated to contain trillions of microorganisms, including bacteria, fungi, and viruses. This community of microorganisms plays a crucial role in our health and well-being, from regulating immune function to digesting food.
The ECS and the microbiome are intrinsically linked and work together to maintain the balance of the organism. Alterations in the microbiome may affect endocannabinoid production and function, which in turn may impact functions regulated by the ECS, such as inflammation and immune function.
Some research suggests that cannabinoids, including CBD, may influence the composition and function of the microbiota. In one study, mice treated with CBD showed changes to their gut microbiome, with a decrease in the abundance of bacteria that may be associated with inflammation and an increase in bacteria that may be beneficial for gut health.
These findings suggest that cannabinoids could have the potential to influence the health and function of the microbiome , which in turn could have implications for digestion and overall health.
Bottom Line: CBD a Promising Aid for Digestion and Stress
In summary, CBD has the potential to offer various benefits for digestion and stress . Although the research is still ongoing, preliminary studies are promising and suggest that CBD may be a valuable addition to digestive wellness and stress management strategies.
I must also tell you to be careful with lactation and pregnancy issues, that here I leave you an article .
It is important to remember that CBD is not a magic bullet and it is essential to consider other aspects of lifestyle, such as diet, exercise and stress management, to maintain healthy digestive function and a balanced mood.
#CBD #Digestion #StressRelief #comersano
Behavior of digestion, in vitro and in vivo bioavailability of cannabidiol in emulsions stabilized by whey protein-maltodextrin conjugate: impact of carrier oil
Ce Wang 1, chao dong 2, Ying Cong Lu 3, kalev freeman 4, Cuina Wang 5, Mingruo Guo 6
- "The Effects of Food on Cannabidiol Bioaccessibility", The Effects of Food on Cannabidiol Bioaccessibility
- Pertwee, R. G. (2008). The diverse CB1 and CB2 receptor pharmacology of three plant cannabinoids: Δ9-tetrahydrocannabinol, cannabidiol and Δ9-tetrahydrocannabivarin. British journal of pharmacology, 153(2), 199-215.
- Lipid-based formulations to increase the bioavailability of cannabidiol: in vitro digestion tests, preclinical evaluation and clinical trial
- Sharkey, KA, & Wiley, JW (2016). The Role of the Endocannabinoid System in the Brain–Gut Axis. Gastroenterology, 151(2), 252-266.
- Russo, E.B. (2008). Cannabinoids in the management of difficult to treat pain. Therapeutics and Clinical Risk Management, 4(1), 245–259.
- Holleran, G., Scalisi, G., Cani, PD, & Lopetuso, LR (2020). Microbiota-host interactions in health and diseases: from gut to brain and more. Therapeutic Advances in Gastroenterology, 13, 1756284820945272.
- Al-Ghezi, ZZ, Miranda, K., Nagarkatti, M., & Nagarkatti, PS (2019). Combination of cannabinoids, Δ9-tetrahydrocannabinol and cannabidiol, ameliorates experimental multiple sclerosis by suppressing neuroinflammation through regulation of miRNA-mediated signaling pathways. Frontiers in immunology, 10, 1921.
- Klein, TW (2005). Cannabinoid-based drugs as anti-inflammatory therapeutics. Nature Reviews Immunology, 5(5), 400-411.
- "The endocannabinoid system as a target for the treatment of neurodegenerative diseases", Scotter, EL, Abood, ME, & Glass, M. (2010). The endocannabinoid system as a target for the treatment of neurodegenerative disease . British journal of pharmacology, 160(3), 480-498.
- Zou, S., & Kumar, U. (2018). Cannabinoid receptors and the endocannabinoid system: signaling and function in the central nervous system. International journal of molecular sciences, 19(3), 833.
- Acharya, N., Penukonda, S., Shcheglova, T., Hagymasi, AT, Basu, S., & Srivastava, PK (2017). Endocannabinoid system acts as a regulator of immune homeostasis in the gut . Proceedings of the National Academy of Sciences, 114(19), 5005-5010.